Once Upon a Time is an American fairy tale drama series on ABC. The show takes place in the fictional seaside town of Storybrooke, Maine, whose residents are characters from various fairy tales transported to the "real world" town and robbed of their real memories by a powerful curse. Episodes typically feature a primary storyline in Storybrooke, as well as a secondary storyline from another point in a character's life before the curse was enacted.
Characters from 101 Dalmatians occasionally make appearances in the series. These include Cruella de Vil, who is one of the Queens of Darkness, who are the main antagonists of season four, and Pongo, who is the pet of Jiminy Cricket in Storybrooke.
- Pongo appears as the pet of Jiminy Cricket and lives in Storybrooke.
- Cruella is one of the main antagonists of Season 4 and the secondary antagonist of Season 5b. In this continuity, she has the ability to persuade and control animals, using magic given to her by the Author. She is also pure evil here. She is killed by Emma Swan in Season 4 and returns in Season 5 as a resident of the Underworld. She becomes Mayor after the departure of the Queen of Hearts but becomes Ruler of the Underworld for a short period after Hades' departure, until King Arthur seizes control from her to make it a better place.